| Message: | Acetylation of histones including histone H4 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) play critical roles in controlling histone acetylation. Histone acetylation is tightly involved in cell cycle regulation, cell proliferation, and apoptosis. Reversible acetylation of nucleosomal histones H4 generally is believed to be correlated with potential transcriptional activity of eukaryotic chromatin domains. Histone H4 acetylation may be increased by inhibition of HDACs and decreased by HAT inhibition. There are very few methods used for measuring histone H4 acetylation. The Histone H4 Acetylation Assay Kit addresses this problem by providing a unique procedure to measure acetylation of histone H4.
https://www.creativebiomart.net/histone-h4-acetylation-assay-kit-463119.htm |
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