| Message: | Acetylation of histones including histone H3 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) play a critical role in controlling histone H3 acetylation. Histone acetylation is tightly involved in cell cycle regulation, cell proliferation and apoptosis. An imbalance in the equilibrium of histone acetylation has been associated with tumorigenesis and cancer progression. Histone H3 acetylation may be increased by inhibition of HDACs and decreased by HAT inhibition. Currently there are few methods used for measuring histone H3 acetylation. The Histone H3 Acetylation Assay Kit addresses this problem by providing a unique procedure to measure acetylation of histone H3.
https://www.creativebiomart.net/histone-h3-acetylation-assay-kit-463108.htm |
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