my account  log out
 

Human type 4 Collagen [His]

Create: 04/27/2019
Expired Date:never
Category: Medical testing [Health&Medical&Pharmaceutical]
Message:Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In the Goodpasture syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. https://www.creative-diagnostics.com/Recombinant-Human-Collagen-Type-IV-Alpha-3-His-tagged-5445-427.htm
City:New York[US] 
Location:
 
Aug 27 2019Recombinant HCV core 24 genotype 1b497
Aug 27 2019Recombinant HCV core 2-119aa genotype 2499
Aug 27 2019Active hepatitis c virus Hepatitis C virus Genotype 1b NS3 protein513
Aug 27 2019Hepatitis C Virus Hepatitis C Virus NS4A protein482
Aug 27 2019Active Hepatitis C Virus Core 1a protein439
Aug 27 2019Hepatitis C Virus Hepatitis C Virus NS4 protein485
Aug 27 2019Hepatitis C Virus Hepatitis C Virus Core Antigen protein475
Aug 27 2019Hepatitis C Virus Hepatitis C Virus NS5a protein497
Aug 27 2019Active hepatitis c virus Hepatitis C Virus NS3 (mutated A156 T) protein486
Aug 27 2019Hepatitis C Virus Hepatitis C Virus protein465

return back

Copyright © toextrade Inc. All rights reserved. Contact us