| Message: | Vortioxetine hydrobromide
CAS 508233-74-7
White powder
Assay: 99%
Chemical name: 1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine, hydrobromide
Description
Vortioxetine hydrobromide is indicated for the treatment of major depressive disorder (MDD) 。
The recommended starting dose is 10 mg administered orally once daily without regard to meals.
The dose should then be increased to 20 mg/day, as tolerated.
Consider 5 mg/day for patients who do not tolerate higher doses .
Vortioxetine can be discontinued abruptly. However, it is recommended that doses of 15 mg/day or 20 mg/day be reduced to 10 mg/day for one week prior to full discontinuation if possible.
The maximum recommended dose is 10 mg/day in known CYP2D6 poor metabolizers. |
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