Message: | Antifungal Agent CAS 22832-87-7 Miconazole Nitrate
Basic Information:
Product Name Miconazole Nitrate
CAS 22832-87-7
EINECS 245-256-6
Assay 99.0%
Appearance White Crystalline Powder
Molecular Formula C18H15Cl4N3O4
Molecular weight 479.14
Grade Pharmaceutical Grade
Storage Shading, Confined Preservation
Product Description:
Miconazole is an imidazole antifungal agent, developed by Janssen Pharmaceutica, commonly applied topically to the skin or to mucous membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. It can also be used against certain species of Leishmania protozoa which are a type of unicellular parasites that also contain ergosterol in their cell membranes. In addition to its antifungal and antiparasitic actions, it also has some antibacterial properties. It is marketed in various formulations under various brand names.
Medical Uses:
Miconazole is mainly used externally for the treatment of athlete's foot, ringworm, and jock itch. Internal application is used for oral or vaginal thrush (yeast infection). The oral gel may also be used for the lip disorder angular cheilitis.
In the UK, miconazole may be used to treat neonatal oral thrush, while the alternative nystatin is only licensed for patients over the age of one month, but drug interactions are possible.
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