| Message: | Ropivacaine, an amide local anesthetic, is mainly applied for surgical anesthesia: epidural anesthesia (including cesarean section with epidural anesthesia). Acute pain management: for postoperative or analgesia, continuous epidural infusion can also be an intermittent medication.
Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Cocaine, Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest).
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