| Message: | Basic Info.
Product Name: Eplerenone
Chemical Name: Pregn-4-ene-7,21-dicarboxylic acid 9,11-epoxy-17-hydroxy-3-oxo gamma-
lactone methyl ester
Molecular Formula: C24H30O6
Molecular weight: 414.49
CAS NO.: 107724-20-9
Appearance: white crystalline powder; slightly soluble in water.
Standard: Enterprise Standard
Description:
Eplerenone (INN) /plrnon/ is an aldosterone antagonist used as an adjunct in the management of chronic heart failure. It is similar to the diuretic spironolactone, though it is much more selective for the mineralocorticoid receptor in comparison (i.e., does not possess any antiandrogen, progestogen, or estrogenic effects), and is specifically marketed for reducing cardiovascular risk in patients following myocardial infarction. It was marketed byPfizer under the trade name Inspra but is now only available as a generic in every country except the United Kingdom. Eplerenone is a potassium-sparing diuretic, meaning that it helps the body get rid of water but still keep potassium.
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