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Product Name: Vinblastine Sulfate
CAS: 143-67-9
Standard: USP /EP /BP 99.5%
MF: C46H60N4O13S
MW: 909.0526
Appearance: White crystalline powder
Introduction
Mainly used for the treatment of solid tumor. For malignant lymphoma, testicular neoplasm and choriocarcinoma curative effect is better. For lung, breast, ovarian, skin cancer, renal mother cell tumor and monocytes leukaemia also have certain curative effect.
Pharmacology: Vinblastine Vinca plants for the oleander extract has anti-cancer activity of an alkaloid. Major inhibition of tubulin polymerization, preventing the formation of spindle microtubules, so stop in MID-mitosis. Role in the cell membrane can also interfere with membrane transport of amino acids, protein synthesis was inhibited, also inhibited RNA synthesis.
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