Message: | This product is a major role in the pyrimidine antimetabolites S proliferating cells by inhibition of cellular DNA synthesis, interfere with cell proliferation. Cytarabine into the human body after the kinase phosphorylated cytarabine triphosphate into muscle cytarabine diphosphate, the former can strongly inhibit the synthesis of DNA polymerase, which can inhibit converted to cytidine diphosphate deoxycytidine diphosphate, thereby inhibiting polymerization and synthesis of cellular DNA.
This product is a cell cycle-specific drugs, proliferating cells in S phase effects on the most sensitive to inhibition of RNA and protein synthesis is weak.
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