| Message: | Chemical Properties Off-White Crystalline Solid
Usage An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.
Usage antineoplastic, inhibits ribonucleoside diphosphate reductase
General Description Odorless or almost odorless white to off-white crystalline solid. Tasteless.
Air & Water Reactions Water soluble.
Reactivity Profile An amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Fire Hazard Flash point data for Hydroxyurea are not available; however, Hydroxyurea is probably combustible.
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