| Message: | Refined Powder Female Steroidal Progestin Hormone CAS 595-33-5 Megestrol Acetate
Basic information:
Product Name: Megestrol acetate
Synonyms: 17-(acetyloxy)-6-methylpregna-4,6-diene-3,20-dione;
6-dehydro-6-methyl-17-alpha-acetoxyprogesterone;
6-Dehydro-6-methyl-17alpha-acetoxyprogesterone
CAS: 595-33-5
MF: C24H32O4
MW: 384.51
EINECS: 209-864-5
Product Categories: Active Pharmaceutical Ingredients;Antitumors for
Research and Experimental Use;Biochemistry;Hydroxyketosteroids;Steroids;
Product Description :
Megestrol acetate (INN, USAN, BAN, JAN) (abbreviated as MGA or MA, and sold mainly under the brand names Megace and Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects.
Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same as megestrol, which is a closely related but different compound.
Megestrol acetate has powerful antiandrogenic and antiestrogenic effects in humans at sufficient doses, capable of decreasing circulating androgen and estrogen concentrations to castrate levels in both sexes and significantly lowering the expression of the androgen receptor (AR) and the estrogen receptor (ER) in the body.
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