| Message: | Basic info:
Avanafil
Assay: 99% min.
CAS: 330784-47-9
Molecular Formula:C23H26ClN7O3
Molecular Weight:483.9506
Character: White to Off-White Cyrstalline Solid.
Descripition:
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are , tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.
Application:
Treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM. A phosphodiesterase. |
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