Message: | Betadex Sulfobutyl Ether Sodium is a sodium salt produced when betacyclodextrin is alkylated by 1,4-butanesulfonic acid lactone under alkaline conditions. It is an anion, highly water-soluble betacyclodextrin derivative. Sulfobutyl betacyclodextrin sodium can be well combined with the drug molecules to form non-covalent complex, thereby enhancing the stability , water solubility , and safety of the drug , reducing its renal toxicity, easing drug hemolysis, controlling drug release rate, covering bad smell, etc. Compared with betacyclodextrin, sulfobutyl betacyclodextrin sodium has a higher water solubility, smaller hemolytic effect, and lower renal toxicity, which make it a new pharmaceutical excipient with very broad application prospects. |