Message: | I.IDFP basic Characters:
Name: IDFP
CAS: 615250-02-7
Molecular Formula: C15H32FO2P
Molecular Weight: 294.391
Melt Point:
Storage Temp: -20°C
Color:
How IDFP works?
IDFP is an irreversible inhibitor for a number of different enzymes that normally serve to break down neurotransmitters, however the long alkyl chain of IDFP makes itdramatically weaker as an inhibitor of acetylcholinesterase (AChE), while it is a potent inhibitor of two enzymes monoacylglycerol lipase (MAGL), the primary enzyme responsible for degrading the endocannabinoid 2-arachidonoylglycerol (2-AG), and fatty acid amide hydrolase (FAAH), the primary enzyme that degrades the other mainendocannabinoid anandamide. An organophosphorus compound that dually inhibits MAGL and FAAH with IC50 values of 0.8 and 3 nM, respectively.1 At 10 mg/kg, IDFP elevates brain levels of 2-AG and AEA more than 10-fold, and decreases levels of arachidonic acid by 10-fold.
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