| Message: | The Y maze is widely used to assess behavioral task in preclinical research for studying spatial learning and memory. The use of Y maze tests includes spontaneous alternation test and recognition memory test. These tests have been shown to be sensitive to hippocampal damage, gene manipulations, and amnestic drugs. Creative Biolabs utilizes these Y maze paradigms to evaluate novel drugs for their effects on cognition or test the memory function in rodents.
Y Maze spontaneous alternation is a behavioral test based on the animals' natural curiosity for exploration. The animals typically tend to explore a new arm of the maze rather than returning to one that was previously visited. Many parts of the brain, including the hippocampus, septum, basal forebrain, and prefrontal cortex, are involved in this task. https://www.creative-biolabs.com/drug-discovery/therapeutics/y-maze-test.htm. |
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