| Message: | Creative Biolabs now offers a comprehensive range of in vivo pharmacokinetic (PK) investigative studies and screening studies that includes quick turnaround PK screening for lead optimization or formulation evaluation, which could be conducted in rodents and non-rodents, such as mice, rats, rabbits and non-human primates (NHPs). Our scientists go all out to provide well-designed PK studies with reliable data to formulate the most efficient and cost-effective proposal for your preclinical studies.
Successful drug discovery depends on the selection of drug candidates with appropriate preclinical efficacy and safety profiles, as well as good in vivo PK properties. A thorough investigation of the pharmacokinetics in preclinical species will provide much significant information for the prediction of PK in human bodies, as well as for the prediction of a sensible and safe dosage prior to first-in-human clinical trials. In vivo PK investigative or screening studies contribute to the selection of lead compounds with desired bioavailability profiles for further investigation during drug development. In general, in vivo PK investigative or screening studies can provide a more human-relevant figure of how a drug is likely to behave in the human body, and what dose levels should be considered for clinical trials. https://www.creative-biolabs.com/drug-discovery/therapeutics/investigative-or-screening-studies.htm
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