Message: | As a pioneer company in drug discovery process, Creative Biolabs has gained a wealth of experience in providing PK/PD services for global pharmaceutical company and independent researcher. Leveraging our extensive experience and advanced technology, now we can perform quantitative tissue distribution studies to help our worldwide customers with the evaluation of their drug candidates. Our professional staffs are responsible for study designs and data analysis according to your requirements.
Tissue distribution study plays a vital role in drug development programs as it can provide important information on the distribution of test compound into tissues of the animals selected for preclinical assessment. Theoretically, each part of the body can receive different doses of the drug and remain the drug in the different amount of time. Traditionally, investigations are performed by conventional methods, such as tissue dissection, total radioactivity determination, and LC-MS-MS/QPCR. However, the appearance of quantitative whole-body autoradiography (QWBA) has reformed the drug distribution research by utilizing phosphor imaging technology and offering high-resolution images. https://www.creative-biolabs.com/drug-discovery/therapeutics/quantitative-tissue-distribution-studies.htm. |