| Message: | Quantitation of drugs and their metabolites in human and animal tissues is an important aspect of drug discovery and development. In the drug-discovery setting, tissue analyses are needed as part of target organ penetration studies for in vivo pharmacological assessments. In particular, drug concentrations in tissues of preclinical species can be used for human dosimetry prediction and the primary or secondary endpoints for pharmacological effect and safety monitoring. Therefore, bioanalysis of drugs and their metabolites in samples can play an important role in understanding the pharmacological and toxicological properties of new drug candidates. https://www.creative-biolabs.com/drug-discovery/therapeutics/pk-bioanalysis-for-the-samples.htm
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