| Message: | The ability of cancer immunotherapy to harness the body's own immune system to target and kill tumor cells has proven to be clinically formidable. To date, immune checkpoint blockade therapies have been demonstrated to be of substantial clinical benefit in cancer patients. V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is a novel inhibitory immune-checkpoint molecule that suppresses CD4+ and CD8+ T cell activation when expressed on antigen-presenting cells and represents another compensatory inhibitory pathway in tumors. Creative Biolabs offers the best guarantee in the industry of genetically engineering models and has successfully launched an optimized Magic™ “humanized” animal platform to offer specialty humanized VISTA immune checkpoint knock-in mice for our clients all over the world. https://www.creative-biolabs.com/drug-discovery/therapeutics/magic-humanized-vista-immune-checkpoint-knock-in-mice.htm. |
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