| Message: | BLI technology refers to determining the biomolecular mutual effect. This technique is an optical analytic approach analyzing the interference pattern of white light reverberated from two surfaces: an inner reference layer, and a layer of settled protein on the biosensor tip. A variation in the interference pattern is induced by any altering in the number of molecules combined the biosensor tip. In this case, interactions can be gauged in real time, offering the capacity to supervise binding specificity, the ratio of association and dissociation, concentration, with fidelity and accuracy. In addition, only molecules combining with or separating from the biosensor are capable of changing the interference pattern and produce a reaction profile on the BLI system. However, molecules without binding, vary in the refractive index of the ambient medium or vary in flow rate have no effect on the interference pattern. https://www.creative-biolabs.com/drug-discovery/therapeutics/biolayer-interferometry-bli.htm. |
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