| Message: | G-protein-coupled receptors (GPCR), known as 7 transmembrane receptors, are the largest family of cell surface receptors and account for approximately 4% of the protein-coding human genome. They participate in a variety of important physiological functions and are considered one of the most successful therapeutic targets for a broad spectrum of diseases. Therefore, GPCRs represents the largest family of druggable targets for therapeutic interventions, constituting over 50% of the current therapeutic agents on the market. Given their appealing properties and great therapeutic potential, Creative Biolabs has established an innovative Magic™ GPCR cell line platform to study compound functionalities in early development stage. Incorporated with a unique biosensor system, GPCR activities can be monitored via second messenger molecules (i.e. Ca2+, DAG, cAMP). In addition, currently we also provide a full range of Magic™ GPCR multiplex cell lines capable of detecting multiple pathway activities. https://www.creative-biolabs.com/drug-discovery/therapeutics/magic-multiplex-gpcr-cell-lines.htm. |
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