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Magic™ M5 Stable Cell Line

Create: 07/31/2019
Expired Date:never
Category: Immunoglobulins [Chemical]
Message:The muscarinic acetylcholine receptors belong to the GPCR family that interact with G-proteins to initiate intracellular responses. It is composed of five different subtypes: M1, M2, M3, M4, and M5 receptors. After activated by an agonist, M5 will accelerate the rate of phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolysis and increase the formation of inositol 1,4,5-trisphosphate (InsP3) and diacylglycerol (DAG). It has been shown that these products act as second messengers by activating protein kinase(s) C (PCK) and mobilizing Ca2+ from intracellular stores respectively. https://www.creative-biolabs.com/drug-discovery/therapeutics/magic-m5-stable-cell-line.htm.
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