Message: | Immunotherapy with single immune checkpoint blockade has shown remarkable rapid and durable clinical benefit for various cancer patients, providing a new method of immuno-oncology for cancer treatment. Nowadays, combining immunotherapeutic antibodies in cancer treatment has shown benefits over single agents. The prospect of combining agonistic with antagonistic agents is of great potential since this combination therapy represents a real immunologic opportunity to ‘step on the gas' while ‘cutting the brakes'. As always being a leading company providing genetically customized mouse models, Creative Biolabs develops the Magic™ dual immune checkpoint “humanized” mouse models for your study of novel antibody drug discovery, including the humanized CTLA-4/OX40 dual immune checkpoint knock-in mice with the best guarantee in the industry. https://www.creative-biolabs.com/drug-discovery/therapeutics/magic-humanized-ctla-4-ox40-dual-immune-checkpoint-knock-in-mice.htm. |