| Message: | Amphetamine is a central nervous system stimulant marketed under the brand name Evekeo, among others. It is used in the treatment of attention deficit hyperactivity disorder, narcolepsy, and obesity. Amphetamine was discovered in 1887 and exists as two enantiomers: levoamphetamine and dextroamphetamine.
IUPAC ID: 1-phenylpropan-2-amine
Drug class: CNS stimulant, anorectic
Duration of action: IR dosing: 3–6 hours; XR dosing: 8–12 hours
Onset of action: IR dosing: 30–60 minutes; XR dosing: 1.5–2 hours
Other names: α-methylphenethylamine
Metabolism: CYP2D6, DBH, FMO3
Elimination half-life: D-amph: 9–11 hours; L-amph: 11–14 hours; pH-dependent: 7–34 hours |
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