| Message: | Ethyl Oleate CAS: 111-62-6
Product Name: ETHYL OLEATE
Other Name : EO
CAS: 111-62-6
MF: C20H38O2
MW: 310.51
EINECS: 203-889-5
Chemical Properties:
mp -32 °C(lit.)
bp 216-218 °C15 mm Hg
density 0.87 g/mL at 25 °C(lit.)
FEMA 2450
refractive index n20/D 1.451(lit.)
Fp >230 °F
storage temp. -20°C
Sensitive Light Sensitive
Appearance clear pale yellow oily liquid
Safety Information:
Safety Statements 23-24/25-22
WGK Germany 2
RTECS RG3715000
F 10-23
Description:
Ethyl oleate is one of the fatty acid ethyl esters (FAEE) that is formed in the body after ingestion of ethanol. There is a growing body of research literature that implicates FAEEs such as ethyl oleate as the toxic mediators of ethanol in the body (pancreas, liver, heart, and brain). Among the speculations is that ethyl oleate may be the toxic mediator of alcohol infetal alcohol syndrome. The oral ingestion of ethyl oleate has been carefully studied and due to rapid degradation in the digestive tract it appears safe for oral ingestion. Ethyl oleate is not currently approved by the U.S. Food and Drug Administration for any injectable use. However, it is used by compounding pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare the daily doses of progesterone in support of pregnancy. Studies which document the safe use of ethyl oleate in pregnancy for both the mother and the fetus have never been performed.
Application:
Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances
such as steroids. It also finds use as a lubricant and a plasticizer.Ethyl oleate is regulated as a food additive by the Food and Drug Administration under "Food Additives Permitted for Direct Addition to Food for Human Consumption. Ethyl oleate is a fatty acid ester formed by the condensation of oleic acid andethanol. It is a colorless to light yellow liquid. |
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