| Message: | Pramoxine Hydrochloride CAS: 637-58-1
Product Name: Pramoxine Hydrochloride
Synonyms: proctofoam; PRAMOXINE HCL; TRONOTHANE HYDROCHLORIDE
CAS: 637-58-1
MF: C17H28ClNO3
MW: 329.86
EINECS: 211-293-1
Appearance: White powder
Description and Application:
Pramoxine Hydrochloride is a combination of a corticosteroid and an anesthetic.It is used to decrease swelling, itching and pain that is caused by minor skin irritations or hemorrhoids.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in man. Like other local anesthetics, paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.
Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches. Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.
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