| Message: | Sunifiram CAS: 314728-85-3
Product Name: Sunifiram
Alias: DM-235
CAS: 314728-85-3
MF: C14H18N2O2
MW: 246.30492
Appearance: Off-white to white crystalline powder
Description:
Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).
Application:
This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation.
Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.
Benefit:
1. Increases energy levels, allowing users to feel more motivated and eliminate
2. Increase Levels of concentration increase, and users feel less distracted by external stimuli
3. It also enhances long-term potentiation, which is the forming of new connections regarding memory storage.
4. It has some anxiolytic benefits. Feeling more relaxed is beneficial when trying to focus.
|
my account
