| Message: | Glabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract. It has been reported to posses varies biological activities including strong antioxidant activity, antioxidant against LDL oxidation, anti-Helicobacter pylori properties, estrogen-like activity and antinephritic and radical scavenging activities. It retains anti-inflammatory abilities to regulate the synthesis and activity of iNOS under high-glucose levels, implying that a Glabridin supplement may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction. It inhibited the invasion of human HCC cells and may have potential as a chemopreventive agent against liver cancer metastasis. It exhibits antiplasmodial activity and is suitable for developing antimalarial agent from a cheap and sustainable source. It may possess a therapeutic effect on metabolic disorders, such as diabetes and hyperglycemia, by modulating glucose metabolism through AMPK in skeletal muscle cells.www.bocsci.com/glabridin-cas-59870-68-7-item-5-465183.html
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