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Alectinib

Create: 09/23/2019
Expired Date:never
Category: Chemical
Message:Alectinib, also known as AF802, or CH5424802 or RO5424802, is a potent, selective, and orally available ALK inhibitor with a unique chemical scaffold, showing preferential antitumor activity against cancers with gene alterations of ALK. CH5424802 inhibited ALK L1196M, which corresponds to the gatekeeper mutation conferring common resistance to kinase inhibitors, and blocked EML4-ALK L1196M-driven cell growth. Results support the potential for clinical evaluation of CH5424802 for the treatment of patients with ALK-driven tumors.https://www.bocsci.com/alectinib-cas-1256580-46-7-item-454466.html
City:New York[US] 
Location:
 
Sep 23 2019Y-27632 2HCl232
Sep 23 2019BMS-911543248
Sep 23 2019JQ-1 cas 1268524-70-4235
Sep 23 2019Alectinib230
Sep 23 2019Tubastatin A238
Sep 23 2019FLLL32236
Sep 23 2019Thiazovivin239
Sep 23 2019Alpelisib240
Sep 23 2019Ribociclib218
Sep 23 2019Midostaurin217

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