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Alectinib

Create: 09/23/2019
Expired Date:never
Category: Chemical
Message:Alectinib, also known as AF802, or CH5424802 or RO5424802, is a potent, selective, and orally available ALK inhibitor with a unique chemical scaffold, showing preferential antitumor activity against cancers with gene alterations of ALK. CH5424802 inhibited ALK L1196M, which corresponds to the gatekeeper mutation conferring common resistance to kinase inhibitors, and blocked EML4-ALK L1196M-driven cell growth. Results support the potential for clinical evaluation of CH5424802 for the treatment of patients with ALK-driven tumors.https://www.bocsci.com/alectinib-cas-1256580-46-7-item-454466.html
City:New York[US] 
Location:
 
Sep 23 2019Y-27632 2HCl237
Sep 23 2019BMS-911543254
Sep 23 2019JQ-1 cas 1268524-70-4241
Sep 23 2019Alectinib236
Sep 23 2019Tubastatin A244
Sep 23 2019FLLL32241
Sep 23 2019Thiazovivin246
Sep 23 2019Alpelisib247
Sep 23 2019Ribociclib223
Sep 23 2019Midostaurin224

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