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FLLL32

Create: 09/23/2019
Expired Date:never
Category: Chemical
Message:FLLL32, a novel curcumin analogue, is a potent STAT3 inhibitor. FLLL32 specifically reduced STAT3 phosphorylation at Tyr705 (pSTAT3) and induced apoptosis at micromolar amounts in human melanoma cell lines and primary melanoma cultures. FLLL32 promoted loss of cell proliferation at lower concentrations than curcumin leading to caspase-3- dependent apoptosis. FLLL32 may have potential for targeting multiple myeloma, glioblastoma, liver cancer, and colorectal cancer cells expressing constitutive STAT3 signaling.https://www.bocsci.com/flll32-cas-1226895-15-3-item-462347.html
City:New York[US] 
Location:
 
Sep 23 2019Y-27632 2HCl232
Sep 23 2019BMS-911543248
Sep 23 2019JQ-1 cas 1268524-70-4235
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Sep 23 2019Tubastatin A238
Sep 23 2019FLLL32237
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Sep 23 2019Ribociclib218
Sep 23 2019Midostaurin217

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