Message: | In vacuum blood collection tubes containing coagulant, fibrin precipitated filaments and lumps sometimes appear, which is caused by the unstandardized use of coagulation blood collection tubes. Choosing a coagulant with too fast coagulation speed in the preparation of vacuum blood collection tubes will cause fibrin to shrink too fast and fragile red blood cells will easily fragment and cause mild hemolysis. Generally, the precipitation of fibrin has the following reasons:
Use procoagulant blood collection tube or separation gel to promote coagulation blood collection tube. To make the coagulant evenly distributed in the blood, it must be slightly inverted and mixed 4-5 times to make the center of the blood collection tube and the surrounding blood coagulate at the same time. If the blood is not completely coagulated and then centrifuged, it can cause the precipitation of fibrin. The upper part of the serum appeared jelly-like and fragmented, mixed with the blood. Fibrin filaments are caused by the fact that fibrin has not yet fully contracted.
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