| Message: | When the epidemic is waiting for an opportunity again, to quickly control the spread of the virus, nucleic acid testing has become the only way to go, and it has also attracted attention from all walks of life. However, there are many factors that affect the results of nucleic acid testing, including sample collection location, collection method, storage and transportation process, nucleic acid extraction operation, and so on. Among them, the stability of the sample is a key link. How to quickly inactivate the virus and protect the viral nucleic acid from being degraded, maintaining the stability of the virus sample storage solution has become a top priority.
Step 2: Inhibit enzyme activity and escort the "ID card"
After the shell is lysed, the RNA of the new coronavirus is free in the preservation solution. As a single-stranded macromolecule, the stability of RNA is not as immobile as double-stranded DNA. The RNase that exists everywhere in the natural environment is the culprit that causes RNA to hydrolyze and break. Therefore, it is generally considered that the viral RNA that has lost its outer shell protection is
In addition to the inactivated virus storage solution, the virus preservation solution produced by Desheng also has a non-inactivated virus storage solution. It retains the protein coat of the virus and the viral nucleic acid DNA or RNA at the same time, so that the virus has the integrity of the protein epitope and nucleic acid in vitro. Of course, there is a certain risk of infectivity when operating errors. Long-term storage after sampling needs to keep strictly low temperature. Regardless of the virus preservation solution, we need to strictly operate, store or transport in accordance with the requirements when using it. |
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