Message: | Luminol is widely used as a chemiluminescent reagent in chemiluminescence immunoassay biochemical system. Because hemoglobin contains iron, which can catalyze the decomposition of H2O2 and oxidize luminol, luminol reagent containing H2O2 is widely used in criminal investigation, bioengineering, chemical tracing and other fields. Forensic and criminal police around the world use luminol as a color enhancer for bloodstains. It can be used in the collection of crime scene evidence and laboratory blood determination. At the crime scene, the luminol solution is sprayed on the area where there may be residual blood. When the luminol solution encounters hemoglobin, it will release reactive oxygen species, oxidize luminol and emit blue-green light, which can be used for camera photography and evidence collection. This reagent is considered by forensic scientists to be the most sensitive blood test enhancement reagent.
Although luminol reagent has been widely used in blood testing, sequencing and serological analysis, luminol can stimulate eyes, respiratory system and skin by inhalation, ingestion or skin absorption, and its safety has attracted much attention and its use has been affected. At present, studies can only confirm that luminol is a possible mutagen, but no experiments have been carried out on normal human cells, such as human peripheral blood lymphocytes, and the risk of cell damage. Therefore, it is not possible to assess the toxic dose of luminol to human cells. |