| Message: | Acridine esters are a class of chemiluminescent reagents, which have a variety of models. Acridinium esters and related compounds have been widely proven to be high-quality chemiluminescent labels. The stability and detection sensitivity of acridinium esters surpass radioisotopes and label specificity. . According to the different substituents, acridine substituents commonly used as chemiluminescent labels are divided into two categories: acridine esters and acridine sulfonamides. They all share a common acridine ring in their structure. Their luminescence mechanism is the same: in an alkaline H2O2 solution, when the molecule is attacked by hydrogen peroxide ions, unstable dioxyethane is generated, which decomposes into CO2 and electronically excited N-methyl acridine Ketones emit photons with a maximum emission wavelength of 430nm when they return to the ground state.
Chemiluminescence systems such as acridine esters, 1,2-dioxetanes and peroxyoxalates, the combination of chemiluminescence and other technologies such as high performance liquid chromatography, sensor technology and flow injection technology, because It has the advantages of fast analysis speed, simple equipment, high sensitivity and wide linear range. It has been widely used in chemical food safety, biomedicine, environmental testing and other fields. |
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