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Through the above introduction, it can be understood that the mechanism of action of MK677 is to promote the secretion of growth hormone (GH) and islet-like growth factor 1 (IGF-1). MK677 can increase growth hormone (GH) and islet-like growth factor-1 (IGF-1) in the body to improve the body's anabolism, increase the body's protein synthesis, improve muscle mass, and improve the body's bone quality.
MK677 and growth hormone secretagogue (GHS) receptor agonists
Growth hormone secretagogue (GHS) receptor agonists are divided into peptides and non-peptides, and peptides include GHRP-2 and GHRP-6. And MK677 belongs to the oral non-peptide class.
Ghrp-6 and GHRP-2 are the best-known growth hormone releasing peptides (GHRP). They also stimulate growth hormone production by activating ghrelin receptors, but GHRP-6 and GHRP-2 have shorter half-lives and require multiple daily dosing. Furthermore, the peptide structures of GHRP-6 and GHRP-2 make them injectable only. Multiple daily injections can leave visible marks on the skin.
Ghrp-6 was the first ghrelin to be developed, and MK-677 was derived from its molecule. Therefore, MK677 naturally has a growth hormone peptide-like effect.
SARM MK677 is a non-peptide ghrelin (GHS) receptor agonist and a growth hormone secretagogue that is orally available, making it easier to use when switching from injection to oral administration. MK677 also has a longer half-life and can be used once a day, which further improves the user's experience. |
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