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Phase I trials of SARMs RAD 140 demonstrated acceptable safety at doses of 50 mg, 100 mg, and 150 mg per day.
A case of drug-induced liver injury in a 52-year-old white man after taking a supplement containing SARMs RAD 140 was reported, in which liver enzymes returned to normal levels approximately 3 months after discontinuation of the supplement. Since the man also reported drinking whiskey and beer daily and using recreational drugs, and the supplements he used were not SARMs RAD 140 raw powders but also contained LGD 4033 and an unapproved substance, it is not clear that SARMs RAD 140 would cause liver damage.
In the SARMs RAD 140 experiments, there was a good relationship between oral SARMs RAD 140 and liver lipids, and minimal elevation of liver enzymes was seen at doses 10 times higher than the effective dose. Thus, SARMs RAD 140 has little to no hepatotoxicity.
Side effects of SARMs RAD 140 also include testosterone suppression, which manifests in longer SARMs RAD 140 cycles, typically starting at week 8 with decreased libido. However, unlike steroids, SARMs RAD 140 induces testosterone suppression in that SARMs RAD 140 does not affect the HPTA system and testosterone levels spontaneously return to pre-cycle levels within 2 weeks after the end of the SARMs RAD 140 cycles.
Because SARMs RAD 140 does not affect the HPTA system, it is not necessary to use SERM as PCT after use SARMs RAD 140.
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